The Lancet recognised DiRECT type 2 diabetes trial
For a clinical trail to be authorised and accepted by the medical community it must be published in a reputable medical journal, in this case the DiRECT trial was published in The Lancet ref.
What result were published?
On the whole, the study found that by losing weight, on average 10 kilos, showed that they “cured” type 2 diabetes, ref. The trial ran for two years. These were the results:
- The first year of the trail, 36% of participants went into remission
- The second year 70% were in remission.
The surprising discovery about type 2 diabetes
It turns out that the biological nature of type 2 diabetes is due to fat in the pancreas and liver. So, by addressing, these fatty deposits with a low carb diet, under 800 calories per day in the trail. As a result over time the fat in the tissues diminished and in the majority of the participants they went into remission. Remission is when the long-term blood sugar levels (HbA1c) have dropped below 48mmol/mol (6.5%) without the need for diabetic medication. Also, the insulin production at meal time had returned to normal.
Consequently, researchers gave a strong warning to the trial participants who are in remission that if they put the weight back on the disease will return. At the same time, they stressed the importance of a maintenance diet as a preventive measure to continue for the rest of their lives.
A stunning example of one participates story
Take the case of a female participant in spite of being diagnosed with type 2 diabetes eight years before starting the trial, it took her 17 weeks before she went into remission. She was ecstatic that she was able to live a normal life again. To further demonstrate her success four years later she is still not on any diabetes medication.
Further inspiring weight loss benefits
In addition to type 2 diabetes remission, one of the slides from the DiRECT presentation showed research by an obesity surgeon. Where he ran a study following the progress of patients four years after “Laparoscopic Adjustable Gastric Banding,” a weight loss procedure. In summary, the study noted whether the patient’s condition had improved or was it “cured” ref. Here are the conditions that had a positive result, see the graph for more details:
- Hypertension (high blood pressure)
- Sleep apnoea
- Dyspnoea (difficulty breathing)
- General physical activity
- Peripheral Oedema
- Joint Pain
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